Licensed providers, online in all 50 states. Free first consultation. Medications prescribed only when medically necessary.
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Weight & Metabolic Health

Medical weight loss, supervised by licensed providers.

GLP-1 programs for adults living with overweight or obesity, prescribed only when a licensed provider determines they are appropriate, and paired with nutrition, activity and behavioral support. Online, in all 50 states, from $166 a month.

  • Weight that will not budge
  • Constant cravings
  • Prediabetes or insulin resistance
  • Weight regained after dieting
  • Low energy

Free. By phone. Usually available within the hour.

Am I a candidate?What your provider asks

A licensed provider decides. These are the questions they will work through with you.

  • Are you an adult living with overweight or obesity, or with a weight-related metabolic condition such as prediabetes or insulin resistance?
  • Have diet and activity changes alone not produced lasting results?
  • Are you not pregnant, breastfeeding or planning pregnancy?
  • No personal or family history of medullary thyroid cancer or MEN2, and no history of pancreatitis?
  • Are you willing to pair medication with nutrition, activity and regular check-ins?
GLP-1 medications are not suitable for everyone. Only a licensed provider can determine whether a program is appropriate for you.
Plans and pricing

Choose a program and a term.

Every plan includes provider visits, dose adjustments, refills and care-team support. Longer terms cost less per month, ship in one order and never auto-renew.

Weekly injection

Semaglutide program

Provider visits, dose adjustments, refills and care-team support included.

$199/month

Billed monthly. Cancel any time.

  • Licensed provider visit by phone or video
  • Medication shipped from a licensed pharmacy, if prescribed
  • Nutrition, activity and behavioral guidance
Most requested Weekly injection

Tirzepatide program

Dual GLP-1 and GIP receptor medication. Same supervision, same support.

$329/month

Billed monthly. Cancel any time.

  • Licensed provider visit by phone or video
  • Medication shipped from a licensed pharmacy, if prescribed
  • Nutrition, activity and behavioral guidance
Daily tablet, no injection

Oral GLP-1 program

Oral semaglutide from $199/month. Oral tirzepatide from $349/month.

$199/month

Billed monthly. Cancel any time.

  • For patients who would rather not inject
  • Same provider supervision and refills
  • 3-month oral semaglutide supply available in most states

REFUVIA offers both FDA-approved branded medications and compounded alternatives. Which is right for you is determined by your provider during your consultation, based on medical necessity, availability and your preference. Pricing shown is a starting point and varies by the medication prescribed. Compounded medications are prepared by a licensed pharmacy and are not FDA approved. Multi-month packages are dispensed in one shipment and are for patients established on a stable dose.

Results vary. Clinical trial results apply only to the FDA-approved branded medication specifically identified and do not apply to compounded medications. All medications must be prescribed by a licensed provider based on medical necessity.

Compare

Semaglutide, tirzepatide or oral: the practical differences.

What each option is, how it is taken and what it costs. Which one, if any, is appropriate for you is a decision your provider makes with you.

SemaglutideTirzepatideOral GLP-1
What it isA GLP-1 receptor agonistA dual GLP-1 and GIP receptor agonistSemaglutide or tirzepatide as a daily tablet
How it is takenOnce-weekly injection, pen or vialOnce-weekly injection, pen or vialOne tablet daily, no injection
DosingStarted low and stepped up by your provider over the first monthsStarted low and stepped up by your provider over the first monthsStarted low and adjusted by your provider
Starting price$199/month · from $166/month on a 6-month plan$329/month · from $279/month on a 6-month planSemaglutide $199/month · tirzepatide $349/month
Multi-month plans3 and 6 months3 and 6 months3-month oral semaglutide (not in California)
Branded or compoundedEither, decided with your providerEither, decided with your providerCompounded, prepared by a licensed pharmacy
Common side effectsNausea, reflux, constipation or diarrhea, most often early on or after a dose change. Your provider reviews the full risk profile before prescribing.

Results vary. Clinical trial results apply only to the FDA-approved branded medication specifically identified and do not apply to compounded medications. All medications must be prescribed by a licensed provider based on medical necessity.

How a GLP-1 medication works: it mimics a gut hormone that signals fullness to the brain and slows stomach emptying Gutreleases GLP-1 after meals Brainappetite and fullness signals Stomachempties more slowly GLP-1 medication mimics the signal Simplified for education. Individual response varies.
GLP-1 is a hormone the gut releases after eating. GLP-1 receptor agonist medications mimic that signal, act on appetite and fullness signaling, and slow how quickly the stomach empties.
Plain-language education

How GLP-1 medications work.

These medications act on receptors in the brain and gut involved in hunger and fullness, which is why many people describe feeling satisfied with less. They also slow how quickly the stomach empties, which changes how meals feel and is the reason digestive side effects are the most common ones.

They are prescribed as part of a supervised program that includes nutrition, physical activity and behavioral support. Medication alone does not replace evaluation, monitoring or the habits that make progress last.

  • Provider-guided dose steps over the first months
  • Monthly check-ins, adjusted to how you respond
  • Nutrition, activity and behavioral guidance built in
Your first 90 days

What actually happens, week by week.

A conversation, not a commitment

You book a free call with the care team from this site. They explain the program, the pricing, what labs may be needed and what a provider visit involves. You ask anything. Nothing is charged and nothing is decided.

  • Usually within the hour during business hours
  • Bring your history: previous medications, doses, conditions
  • Decide whether to book a provider visit

Who this program is for

  • Adults living with overweight or obesity, or with weight-related metabolic concerns such as prediabetes or insulin resistance
  • People who have tried diet and exercise alone and want a medically supervised plan
  • Patients already on a GLP-1 who want continuity of care with a provider who follows them

Who it is not for

  • Anyone looking for a quick fix or a cosmetic result; these are prescription medications for medical conditions
  • People who are pregnant, breastfeeding or planning pregnancy
  • Patients with a personal or family history of medullary thyroid cancer or MEN2, or a history of pancreatitis
  • Anyone under 18

Side effects and safety

Most common: nausea, reflux, constipation, diarrhea, usually early on or after a dose change. Less common but serious: pancreatitis, gallbladder problems, severe stomach pain, allergic reaction, changes in vision for people with diabetes. Tell your provider about every medication you take, including insulin and other diabetes medications. Report severe or persistent symptoms immediately, and call 911 in an emergency.

All medical decisions are made solely by licensed healthcare professionals. Medications are prescribed only when medically necessary. GLP-1 medications are not suitable for everyone. Results may vary. This page is general education, not medical advice.

Questions & answers

Weight & metabolic health questions.

Is a GLP-1 medication right for me?

That is exactly what the provider visit is for. A licensed provider reviews your history, your goals and, where needed, your labs, and prescribes only when it is medically appropriate. GLP-1 medications are not suitable for everyone.

How much does it cost?

Semaglutide programs are $199 a month, $549 for 3 months or $999 for 6 months ($166 a month). Tirzepatide programs are $329 a month, $897 for 3 months or $1674 for 6 months. Oral options start at $199. Prices include provider visits, dose adjustments, refills and care-team support; the exact price varies by the medication prescribed and is confirmed in the portal before you pay.

Do I need labs before I start?

Often, yes. Labs give your provider a baseline and can surface thyroid, metabolic or hormone issues that affect weight. Your provider orders what is needed and you have it drawn at a lab near you, or you upload recent results.

Semaglutide or tirzepatide, which one?

Both are options a provider may consider. Which one, if either, is appropriate depends on your history, other medications, tolerance and availability. That decision belongs to your provider, not to a website.

What about side effects?

The most commonly reported effects are digestive: nausea, reflux, constipation or diarrhea, usually early on or after a dose change. Less common but serious risks exist and your provider reviews the full profile with you before anything is prescribed. Dosing is adjusted based on how you respond, and you can message the care team any time.

I have taken a GLP-1 before. Can I continue?

Bring your history to the consultation, including the medication, your last dose and when you stopped. Your provider decides whether to continue at a similar dose, restart lower or take a different approach.

What is the difference between the 3-month and 6-month plans and monthly?

Same program, same supervision. Multi-month plans are paid once and dispensed in a single shipment at a lower per-month price, for patients who are established on a stable dose. They do not auto-renew. Monthly plans bill each month and can be cancelled any time. Multi-month packages cannot be combined with coupon codes.

What happens if I want to stop?

Talk to your provider first so you can taper thoughtfully and plan what comes next for nutrition, activity and follow-up. There are no long-term contracts. Monthly plans cancel any time; a multi-month shipment that has already shipped is non-refundable, consistent with pharmacy regulations.

Find out whether a program is right for you, for free.

A short call with the care team, no obligation, and pricing you have already seen. Programs from $166 a month.

Book a free consultation